Publications
2026
- 2026
World Journal of Pediatrics·2026
Individual and temporal differences in the effects of parenteral nutrition duration on neonatal sepsis: a nationwide cohort study, 2013–2022 (Accepted and in press)
Hwang J*, Koh H*, Park J*, Chang YS, Cha WC, Park WY, Ahn SY*, Joo YY*
Medical AICausal Machine LearningElectronic Health RecordsReproductive & Maternal HealthRead article Communication Medicine·2026
Polygenic risk-informed white matter integrity improves deep learning-based prediction of youth depression
Min JJ, Wang HH, Lee E, Kim B, Kin G, Choi SY, Choi K, Hong SH, Jang Y, Rah YU, Kim JY, Han S, Lee KH, Kimg J, Dijk M, Kim J, Chung G, Chung D, Lee SA, Joo YY & Cha J
Polygenic PredictionMedical AIMental HealthRead articleThe Lancet Diabetes & Endocrinology·2026
Multi-ancestry polygenic risk scores for the prediction of type 2 diabetes and complications in diverse ancestries
Huerta-Chagoya A, Kim J, Mandla R, Lu Y, Suzuki K, Petty LE, Ng HK, Choi J, Lee S, Rout M, Lin K, Taylor K, ENSA Genomics Consortium, Genes & Health Research Team, VA Million Veteran Program, Aguilar-Salinas CA, García-García L, González-Villalpando C, Haiman CA, Kim YJ, Kwak SH, Leong A, Loos RJF, Moreno-Estrada A, Morris AP, Orozco L, Rotter JI, Sanghera D, Tusie-Luna T, Voight BF, Vujkovic M, Walters RG, Ge T, Manning AK, Loh M, Below JE, Sim X, Mercader JM, Ng MCY, D-PRISM Consortium
Polygenic PredictionRead article
2025
Journal of Child Psychology and Psychiatry·2025
Individual Differences in Effects of Stressful Life Events on Childhood ADHD: Genetic, Neural, and Familial Contributions
Choi SY, Yi J, Park J, Lee E, Kim BG, Kim G, Joo YY, Cha J
Mental HealthPolygenic PredictionMedical AIRead articleNature Communications·2025
Polygenic architecture of brain structure and function, behaviors, and psychopathologies in children
Joo YY*, Kim BG*, Kim G*, Lee E*, Seo J, Cha J
Medical AIPolygenic PredictionMental HealthImaging Genetics & NeurogeneticsRead articleMolecular Psychiatry·2025
Polygenic scores for psychiatric traits mediate the impact of multigenerational history for depression on offspring psychopathology
Lee E*, van Dijk MT*, Kim BG, Kim G, Murphy E, Talati A, Joo YY, Weissman MM, Cha J
Imaging Genetics & NeurogeneticsMental HealthPolygenic PredictionRead article
2024
Journal of Korean Medical Science·2024
Similar but Distinct Comorbidity Patterns Between Polycystic Ovary Syndrome and Endometriosis in Korean Women: A Nationwide Cohort Study
Jeong HG*, Jeon M*, Ryu KJ, Kim J, Choe BY, Joo YY*, Park H*
Electronic Health RecordsRead articleElife·2024
Gene–environment pathways to cognitive intelligence and psychotic-like experiences in children
Park J, Lee E, Cho G, Hwang H, Kim BG, Kim G, Joo YY*, Cha J*
Imaging Genetics & NeurogeneticsMental HealthPolygenic PredictionRead articleJournal of Psychiatric Research·2024
Multimodal integration of neuroimaging and genetic data for the diagnosis of mood disorders based on computer vision models
Lee S*, Cho Y*, Ji Y, Jeon M, Kim A, Ham BJ*, Joo YY*
Electronic Health RecordsMedical AIImaging Genetics & NeurogeneticsMental HealthPolygenic PredictionRead articleBMC Research Notes 17·2024
Genetic sex validation for sample tracking in next-generation sequencing clinical testing
Hu J, Korchina V, Zouk H, Harden MV, Murdock D, Macbeth A, Harrison SM, Lennon N, Kovar C, Balasubramanian A, Zhang L, G Chandanavelli, D Pasham, R Rowley, K Wiley, ME Smith, A Gordon, GP Jarvik, P Sleiman, MA Kelly, HT Bland, M Murugan, E Venner, E Boerwinkle, eMERGE III consortium, C Prows, L Mahanta, HL Rehm, RA Gibbs, DM Muzny
Electronic Health RecordsGenomics & Multi-omicsRead articleNature genetics·2024
Genetic drivers of heterogeneity in type 2 diabetes pathophysiology
Suzuki K, Hatzikotoulas K, Southam L, Taylor HJ, Yin X, Lorenz KM, Mandla R, Huerta-Chagoya A, Melloni GE, Kanoni S, Rayner NW et al
Genomics & Multi-omicsRead articleHeliyon·2024
Early life stress modulates the genetic influence on brain structure and cognitive function in children
Wang HH*, Moon SY*, Kim H, Kim G, Ahn WY, Joo YY*, Cha J*
Imaging Genetics & NeurogeneticsPolygenic PredictionMental HealthRead article
2023
Journal of Investigative Dermatology·2023
Topical ozone accelerates diabetic wound healing by promoting re-epithelialization via activation of IGF1R-EGFR signaling
Lu JY, Wang XQ, Fu Z, Gao L, Mannam H, Xiang Y, Joo YY, Zeng J, Wang D, Paller AS
Read articleBMC Genomic Data·2023
Overestimated Polygenic Prediction due to Overlapping Subjects in Genetic Datasets
Park DK, Chen M, Kim S, Joo YY, Loving RK, Kim HS, Cha J, Yoo S, Kim JH
Polygenic PredictionRead articlePLoS One·2023
Multi-ancestry genome- and phenome-wide association studies of diverticular disease in electronic health records with natural language processing enriched phenotyping algorithm
Joo YY, Pacheco JA, Thompson WK, Rasmussen-Torvik LJ, Rasmussen LV, Lin FTJ, Andrade M, Borthwick KM, Bottinger E, Cagan A, Carrell DS, Denny JC, Ellis SB, Gottesman O, Linneman JG, Pathak J, Peissig PL, Shang N, Tromp G, Veerappan A, Smith ME, Chisholm RL, Gawron AJ, Hayes MG, Kho AN
Electronic Health RecordsMedical AIGenomics & Multi-omicsRead articleJAMA Network Open·2023
National Trends in sadness and suicidality among Korean adolescents in 2005-2021: a nationwide representative study in 1.1 million individuals
Park S, Yon H, Lee SW, Koyanagi A, Jacob L, Smith L, Cho W, Min C, Lee J, Lee H, Kwon R, Fond G, Boyer L, Rhee SY, Joo YY, Shin JI, Woo HG, Yon DK
Electronic Health RecordsMental HealthRead articleJournal of Child Psychology and Psychiatry·2023
Maternal age at birth and child attention‐deficit hyperactivity disorder: causal association or familial confounding?
Baker BH, Joo YY, Park J, Cha J, Baccarelli AA, Posner J
Polygenic PredictionReproductive & Maternal HealthMental HealthRead article
2022
Frontiers in Endocrinology·2022
Misperception of body weight and associated socioeconomic and health-related factors among Korean female adults: A nationwide population-based study
Joo YY, Kim J, Lee K, Cho GJ, Yi KW
Electronic Health RecordsMedical AIRead articleNature·2022
Genetic diversity fuels gene discovery for tobacco and alcohol use
Saunders GR, Wang X, Chen F, Jang SK, Liu M, Wang C, Gao S, Jiang Y, Khunsriraksakul C, Otto JM, Addison C, et al
Genomics & Multi-omicsRead articleCancer medicine·2022
Statin use in patients with hormone receptor‐positive metastatic breast cancer treated with everolimus and exemestane
Lee K, Noh E, Moon SJ, Joo YY, Kang EJ, Seo JH, Park IH
Electronic Health RecordsRead articleGenes·2022
Cognitive Capacity Genome-Wide Polygenic Scores Identify Individuals with Slower Cognitive Decline in Aging
Joo YY, Cha J, Freese J, Hayes MG
Polygenic PredictionAgingMental HealthMedical AIGenomics & Multi-omicsRead articleNature genetics·2022
Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation
Mahajan A, Spracklen CN, Zhang W, Ng MC, Petty LE, Kitajima H, Yu GZ, Rüeger S, Speidel L, Kim YJ, Horikoshi M et al
Genomics & Multi-omicsRead articleHuman Brain Mapping·2022
The sexual brain, genes, and cognition: A machine‐predicted brain sex score explains individual differences in cognitive intelligence and genetic influence in young children
Kim K, Joo YY, Ahn G, Wang HH, Moon SY, Kim H, Ahn WY, Cha J
Imaging Genetics & NeurogeneticsPolygenic PredictionRead articleJAMA network open·2022
Association of genome-wide polygenic scores for multiple psychiatric and common traits in preadolescent youths at risk of suicide
Joo YY, Moon SY, Wang HH, Kim H, Lee EJ, Kim JH, Posner J, Ahn WY, Choi I, Kim JW, Cha J
Mental HealthPolygenic PredictionMedical AIGenomics & Multi-omicsRead article
2021
Genetics in Medicine·2021
Neptune: an environment for the delivery of genomic medicine
Venner E, Yi V, Murdock DR, Kalla SE, Wu TJ, Sabo A, Li S, Meng Q, Tian X, Murugan M, Cohen M, Kovar C, Wei WQ, Chung WK, Weng C, Wiesner GL, Jarvik GP, Muzny D, Gibbs RA, eMERGE Consortium
Electronic Health RecordsRead articleHuman Genetics and Genomics Advances·2021
Genetic discovery and risk characterization in type 2 diabetes across diverse populations
Polfus LM, Darst BF, Highland H, Sheng X, Ng MCY, Below JE, Petty L, Bien S, Sim X, Wang W, Fontanillas P, Patel Y, Preuss M, Schurmann C, Du Z, Lu Y, Rhie SK, Mercader JM, Tusie-Luna T, González-Villalpando C, Orozco L, Spracklen CN, Cade BE, Jensen RA, Sun M, Joo YY, An P, Yanek LR, Bielak LF, Tajuddin S, Nicolas A, Chen G, Raffield L, Guo X, Chen W-M, Nadkarni GN, Graff M, Tao R, Pankow JS, Daviglus M, Qi Q, Boerwinkle EA, Liu S, Phillips LS, Peters U, Carlson C, Wikens LR, Le Marchand L, North KE, Buyske S, Kooperberg C, Loos RJF, Stram DO, Haiman CA
Electronic Health RecordsGenomics & Multi-omicsRead article
2020
Human Genetics and Genomics Advances·2020
Lessons learned from the eMERGE Network: balancing genomics in discovery and practice
eMERGE Consortium
Electronic Health RecordsRead articleBMJ open·2020
Secular trends in postpartum weight retention from 2003 to 2012: a nationwide, population-based, retrospective, longitudinal study in South Korea
Joo YY, Park JH, Choi S, Cho GJ
Electronic Health RecordsRead articleJournal of Clinical Endocrinology & Metabolism·2020
A polygenic and phenotypic risk prediction for Polycystic Ovary Syndrome evaluated by Phenome-wide association studies
Joo YY, Actkins K, Pacheco JA, Basile AO, Carroll R, Crosslin DR, Day F, Denny JC, Velez Edwards DR, Hakonarson H, Harley JB, Hebbring SJ, Ho K, Jarvik GP, Jones M, Karaderi T, Mentch FD, Meun C, Namjou B, Pendergrass S, Ritchie MD, Stanaway IB, Urbanek M, Walunas TL, Smith M, Chisholm RL, Kho AN, Davis L, Hayes MG, International PCOS Consortium
Electronic Health RecordsPolygenic PredictionMedical AIGenomics & Multi-omicsRead article
2019
The American Journal of Human Genetics·2019
Harmonizing Clinical Sequencing and Interpretation for the eMERGE III Network
eMERGE Consortium
Electronic Health RecordsRead article
2018
Genetic Epidemiology·2018
The eMERGE genotype set of 83,717 subjects imputed to ~40 million variants genome wide and association with the herpes zoster medical record phenotype
Stanaway IB, Hall TO, Rosenthal EA, Palmer M, Naranbhai V, Knevel R, Namjou-Khales B, Carroll RJ, Kiryluk K, Gordon AS, Linder J, Howell KM, Mapes BM, Lin FTJ, Joo YY, Hayes MG, Gharavi AG, Pendergrass SA, Ritchie MD, de Andrade M, Croteau-Chonka DC, Raychaudhuri S, Weiss ST, Lebo M, Amr SS, Carrell D, Larson EB, Chute CG, Rasmussen-Torvik LJ, Roy-Puckelwartz MJ, Sleiman P, Hakonarson H, Li R, Karlson EW, Peterson JF, Kullo IJ, Chisholm R, Denny JC, Jarvik GP, e MN, Crosslin DR
Electronic Health RecordsGenomics & Multi-omicsRead article